Integrated Biology Platform
Delivering comprehensive solutions from early discovery through IND-enabling translational studies
Metabolic Diseases
Metabolic Disease Models
In vivo modeling of metabolic and chronic diseases supporting evaluation of therapeutic efficacy, disease progression, and underlying biological mechanisms across fibrosis, diabetes, and acute organ injury programs.
Diabetes
- Spontaneous Type I diabetes models (e.g., NOD mice)
- Induced Type I and Type II diabetes models
NASH (non-alcoholic steatohepatitis)
- MCD (methionine/choline-deficient) diet-induced model
- Diet-induced NASH models
Fibrosis models
- Liver fibrosis: CCl4-induced and diet-induced models
- Pulmonary fibrosis: bleomycin-induced model
- Renal fibrosis: ureteral ligation and folic acid-induced models
Acute organ injury
- Acute kidney injury: cisplatin-induced and ischemia-reperfusion models
- Acute liver injury: APAP-induced and ConA-induced models
Applications
- Chronic disease modeling and disease progression studies
- Translational pharmacology and efficacy evaluation
- Mechanistic studies of metabolic and fibrotic pathways
- Support for IND-enabling preclinical programs
Reprogramming Cells, Empowering Medicine
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