Our Labs
Mechanism clarification
Target analysis
Protein phosphorylation analysis and degrader efficiency evaluation.
Structural analysis
X-ray crystallography, Cryo-EM and NMR for detailed molecular insights.
Affinity evaluation
SPR, MST, and ITC technologies for binding characterization.
SPR: Surface Plasmon Resonance
MST: Microscale Thermophoresis
ITC: Isothermal Titration Calorimetry
EM: Electron Microscope
NMR: Nuclear Magnetic Resonance Spectroscopy
Guo G, Xu M, Chang Y, Luyten T, Seitaj B, Liu W, Zhu P, Bultynck G, Shi L, Quick M, Liu Q. Ion and pH Sensitivity of a TMBIM Ca2+ Channel. Structure. 2019 Jun 4;27(6):1013-1021.e3. doi: 10.1016/j.str.2019.03.003. Epub 2019 Mar 28.